B-Myb Transcription Factor Activity Assay
- SKU:
- TFAB00072
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- B-Myb
- Reactivity:
- Human
- Mouse
- Rat
Description
B-Myb Transcription Factor Activity Assay
The B-MYB Transcription Factor Activity Assay Kit is a reliable tool for measuring the activity of the B-MYB transcription factor in various samples, including cell lysates and tissue homogenates. This kit offers high sensitivity and specificity, allowing for accurate and reproducible results in a wide range of research applications.B-MYB is a key player in regulating cell cycle progression and cell proliferation, making it an important target for studying oncogenesis and cancer progression. By measuring B-MYB activity, researchers can gain valuable insights into the mechanisms underlying these processes and potentially identify new therapeutic targets for cancer treatment.
Overall, the B-MYB Transcription Factor Activity Assay Kit is essential for researchers looking to investigate the role of B-MYB in cellular processes and its implications for various diseases, including cancer. With its high-quality components and user-friendly protocol, this kit is a valuable asset for any laboratory conducting studies on transcription factor activity.
| Product Name: | B-Myb Transcription Factor Activity Assay |
| Product Code: | TFAB00072 |
| Target: | B-Myb |
| Synonyms: | Myb-like protein 2 |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie B-Myb transcription factor activity assay allows for the detection and qualitative analysis of B-Myb active transcription factors in eukaryotic nuclear or cell lysates.
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | B-Myb: a transcription factor involved in cell cycle progression. Phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 20q13.1 Cellular Component: nucleoplasm Molecular Function:protein binding; chromatin binding; transcription factor activity Biological Process: transcription, DNA-dependent; regulation of cell cycle; positive regulation of transcription from RNA polymerase II promoter; mitotic cell cycle; G2/M transition of mitotic cell cycle |
| NCBI Summary: | The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
| UniProt Code: | P10244 |
| NCBI GenInfo Identifier: | 127584 |
| NCBI Gene ID: | 4605 |
| NCBI Accession: | P10244.1 |
| UniProt Secondary Accession: | P10244,Q53F07, B2RBS5, B7Z8D9, F8W6N6, |
| UniProt Related Accession: | P10244 |
| Molecular Weight: | 75,865 Da |
| NCBI Full Name: | Myb-related protein B |
| NCBI Synonym Full Names: | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NCBI Official Symbol: | MYBL2Â Â |
| NCBI Official Synonym Symbols: | BMYB; B-MYBÂ Â |
| NCBI Protein Information: | myb-related protein B; myb-like protein 2; v-myb myeloblastosis viral oncogene homolog-like 2 |
| UniProt Protein Name: | Myb-related protein B |
| UniProt Synonym Protein Names: | Myb-like protein 2 |
| Protein Family: | Myb-related protein |
| UniProt Gene Name: | MYBL2Â Â |
| UniProt Entry Name: | MYBB_HUMAN |
Related Products
MYB Transcription Factor Activity Assay
MYB (Phospho-Ser12) Transcription Factor Activity Assay
TFE3 Transcription Factor Activity Assay
Smad1 Transcription Factor Activity Assay
RUNX3 Transcription Factor Activity Assay
SIX5 Transcription Factor Activity Assay
SP2 Transcription Factor Activity Assay
GR Transcription Factor Activity Assay
