AZU1 Rabbit Polyclonal Antibody (CAB6132)
- SKU:
- CAB6132
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | AZU1 Rabbit Polyclonal Antibody |
SKU: | CAB6132 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-251 of human AZU1 (NP_001691.1). |
Sequence: | IVGG RKAR PRQF PFLA SIQN QGRH FCGG ALIH ARFV MTAA SCFQ SQNP GVST VVLG AYDL RRRE RQSR QTFS ISSM SENG YDPQ QNLN DLML LQLD REAN LTSS VTIL PLPL QNAT VEAG TRCQ VAGW GSQR SGGR LSRF PRFV NVTV TPED QCRP NNVC TGVL TRRG GICN GDGG TPLV CEGL AHGV ASFS LGPC GRGP DFFT RVAL FRDW IDGV LNNP GPGP A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AZU; HBP; NAZC; hHBP; AZAMP; CAP37; HUMAZUR; AZU1 |
Positive Sample: | LO2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic granule. |
Calculated MW: | 27kDa |
Observed MW: | 35kDa |
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
Purification Method: | Affinity purification |
Gene ID: | 566 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |