The Azurocidin Polyclonal Antibody (CAB6132) is a valuable tool for researchers studying azurocidin, a protein involved in immune regulation and inflammatory responses. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting azurocidin, this antibody allows for the detection and analysis of this important protein in various cell types.Azurocidin is known for its role in modulating immune responses and controlling inflammation, making it a key player in diseases such as cancer and chronic inflammatory conditions.
By studying the function of azurocidin, researchers can gain insights into potential therapeutic targets for these conditions.Overall, the Azurocidin Polyclonal Antibody is a crucial tool for scientists interested in understanding the role of azurocidin in immune regulation and inflammatory processes, and its application in research may lead to the development of novel treatments for various diseases.
Product Name:
AZU1 Rabbit Polyclonal Antibody
SKU:
CAB6132
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-251 of human AZU1 (NP_001691.1).
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
Purification Method:
Affinity purification
Gene ID:
566
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from LO2 cells, using AZU1 Rabbit pAb (CAB6132) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
