The Axin2 Monoclonal Antibody (PAC054234) is a cutting-edge tool for researchers studying the Axin2 protein's role in the Wnt signaling pathway. This antibody, developed through a rigorous immunization process, specifically targets Axin2 in human samples and is validated for use in various applications, including Western blot and immunofluorescence.Axin2 is a key regulator of the Wnt pathway, a crucial signaling cascade involved in development, stem cell maintenance, and tumorigenesis. Dysregulation of Axin2 has been linked to various diseases, including cancer and developmental disorders. By targeting Axin2 with this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially identify novel therapeutic targets.
With its high specificity and sensitivity, the Axin2 Monoclonal Antibody is an indispensable tool for any laboratory conducting research in the fields of developmental biology, cancer biology, and regenerative medicine. Its ability to detect and quantify Axin2 protein levels in different cell types and tissues makes it an essential component of studies aimed at unraveling the complexities of the Wnt pathway and its implications in human health and disease.
Immunohistochemistry of paraffin-embedded human brain tissue using PACO54234 at dilution of 1:100.
Immunofluorescence staining of HepG2 cells with PACO54234 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin), Axin2
