Avpr1b Antibody (PACO33636)
- SKU:
- PACO33636
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Avpr1b Antibody (PACO33636)
The AVPR1B Polyclonal Antibody (PAC033636) is a valuable tool for researchers studying AVPR1B, a receptor for arginine vasopressin known for its role in the regulation of stress response and social behavior. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in various research applications, including Western blotting. By specifically binding to the AVPR1B protein, researchers can easily detect and analyze its expression in different cell types, making it an excellent choice for studies in neuroscience and endocrinology.
AVPR1B, also known as the vasopressin V1b receptor, plays a crucial role in modulating stress-related behaviors, social interactions, and anxiety responses. Its involvement in the regulation of the hypothalamic-pituitary-adrenal axis and social bonding makes it a compelling target for research into psychiatric disorders, stress-related conditions, and social behavior phenotypes. Unraveling the functions of AVPR1B is essential for developing targeted therapies that modulate stress and social behaviors in various pathological conditions.
| Antibody Name: | Avpr1b Antibody (PACO33636) |
| Antibody SKU: | PACO33636 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Vasopressin V1b receptor protein (343-425AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Vasopressin V1b receptor antibody at 2µg/ml Lane 1: EC109 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 47 kDa Observed band size: 47 kDa . |
| Background: | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. |
| Synonyms: | Vasopressin V1b receptor (V1bR) (AVPR V1b) (AVPR V3) (Antidiuretic hormone receptor 1b) (Vasopressin V3 receptor), Avpr1b |
| UniProt Protein Function: | AVPR1B: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral Cellular Component: cytosol; integral to membrane; integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; peptide hormone binding; protein homodimerization activity; vasopressin receptor activity Biological Process: cellular response to hormone stimulus; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; hyperosmotic salinity response; positive regulation of cellular pH reduction; positive regulation of glutamate secretion; positive regulation of vasoconstriction; regulation of systemic arterial blood pressure by vasopressin |
| NCBI Summary: | may play a role in the regulation of cerebrospinal fluid water content [RGD, Feb 2006] |
| UniProt Code: | P48974 |
| NCBI GenInfo Identifier: | 1351393 |
| NCBI Gene ID: | 29462 |
| NCBI Accession: | P48974.1 |
| UniProt Related Accession: | P48974 |
| Molecular Weight: | 47,086 Da |
| NCBI Full Name: | Vasopressin V1b receptor |
| NCBI Synonym Full Names: | arginine vasopressin receptor 1B |
| NCBI Official Symbol: | Avpr1b  |
| NCBI Protein Information: | vasopressin V1b receptor |
| UniProt Protein Name: | Vasopressin V1b receptor |
| UniProt Synonym Protein Names: | AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor |
| Protein Family: | Vasopressin V1b receptor |
| UniProt Gene Name: | Avpr1b  |
| UniProt Entry Name: | V1BR_RAT |
| ELISA Kits |
| Rat AVPR1b / Vasopressin V1b receptor ELISA Kit |
| Rat Vasopressin V1b receptor (Avpr1b) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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