AVPR1B Antibody (PACO00448)
- SKU:
- PACO00448
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
AVPR1B Antibody (PACO00448)
The AVPR1B Polyclonal Antibody (PACO00448) is a valuable tool for researchers studying the AVPR1B receptor, a key player in the regulation of stress response and social behavior. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an essential reagent for various research applications, including Western blotting.The AVPR1B receptor, also known as the arginine vasopressin receptor 1B, is involved in modulating the body's response to stress and influencing social behavior. Dysregulation of this receptor has been linked to various psychiatric disorders, such as anxiety and depression, making it a promising target for therapeutic interventions.
By utilizing the AVPR1B Polyclonal Antibody, researchers can effectively detect and analyze the expression of the AVPR1B receptor in different cell types, providing valuable insights into its functional role in stress response and social behavior. This antibody is a valuable tool for advancing our understanding of the complex mechanisms underlying these processes and holds great potential for the development of novel treatments for stress-related disorders.
| Antibody Name: | AVPR1B Antibody |
| Antibody SKU: | PACO00448 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human AVP Receptor V3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | AVPR1B; AVPR3; VPR3; Vasopressin V1b receptor; V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor |
| UniProt Protein Function: | AVPR1B: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1 Chromosomal Location of Human Ortholog: 1q32 Cellular Component: endosome; integral to plasma membrane; plasma membrane Molecular Function:peptide binding; protein kinase C binding Biological Process: cellular response to hormone stimulus; elevation of cytosolic calcium ion concentration; phospholipase C activation; positive regulation of vasoconstriction; regulation of systemic arterial blood pressure by vasopressin |
| NCBI Summary: | The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P47901 |
| NCBI GenInfo Identifier: | 1351392 |
| NCBI Gene ID: | 553 |
| NCBI Accession: | P47901.1 |
| UniProt Secondary Accession: | P47901,Q5TZ00, B0M0J6, |
| UniProt Related Accession: | P47901 |
| Molecular Weight: | 46,971 Da |
| NCBI Full Name: | Vasopressin V1b receptor |
| NCBI Synonym Full Names: | arginine vasopressin receptor 1B |
| NCBI Official Symbol: | AVPR1BÂ Â |
| NCBI Official Synonym Symbols: | AVPR3Â Â |
| NCBI Protein Information: | vasopressin V1b receptor |
| UniProt Protein Name: | Vasopressin V1b receptor |
| UniProt Synonym Protein Names: | AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor |
| Protein Family: | Vasopressin V1b receptor |
| UniProt Gene Name: | AVPR1BÂ Â |
| UniProt Entry Name: | V1BR_HUMAN |
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