The AVPR1A Polyclonal Antibody (CAB8400) is a valuable tool for research involving the AVPR1A receptor, a key player in the regulation of social behavior and stress response. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications.The AVPR1A receptor, also known as the arginine vasopressin receptor 1A, is involved in mediating the effects of the neuropeptide arginine vasopressin (AVP) in the brain. It plays a crucial role in modulating social behaviors such as bonding, aggression, and affiliation, as well as stress-related responses.
Research into the AVPR1A receptor has implications for understanding various neurobehavioral disorders, including autism spectrum disorders, social anxiety, and depression. By utilizing the AVPR1A Polyclonal Antibody, researchers can elucidate the role of this receptor in normal social behavior and its dysregulation in various psychological conditions. This antibody is a valuable tool for advancing knowledge in the fields of neuroscience and psychology, with potential applications in drug discovery and therapeutic development.
Product Name:
AVPR1A Rabbit Polyclonal Antibody
SKU:
CAB8400
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 349-418 of human AVPR1A (NP_000697.1).
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.
Purification Method:
Affinity purification
Gene ID:
552
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AVPR1A antibody (CAB8400) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
