Avpr1a Antibody (PACO33632)
- SKU:
- PACO33632
- Product Type:
- Antibody
- Reactivity:
- Rat
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Avpr1a Antibody (PACO33632)
The Avpr1a Polyclonal Antibody (PACO33632) is a valuable tool for researchers studying the Avpr1a gene, which encodes for the vasopressin receptor 1A, a G protein-coupled receptor involved in the regulation of social behaviors and stress responses. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in Western blotting and immunohistochemistry applications.The Avpr1a receptor plays a crucial role in modulating social behaviors, including aggression, pair bonding, and parental care. Dysregulation of this receptor has been implicated in various neuropsychiatric disorders, such as autism spectrum disorder and schizophrenia.
By using the Avpr1a Polyclonal Antibody, researchers can investigate the expression and localization of the Avpr1a receptor in different tissues and cell types, advancing our understanding of its role in health and disease.Overall, the Avpr1a Polyclonal Antibody is a valuable research tool for studies exploring the molecular mechanisms underlying social behaviors and stress responses, with potential implications for the development of novel therapeutic strategies targeting the Avpr1a receptor.
| Antibody Name: | Avpr1a Antibody (PACO33632) |
| Antibody SKU: | PACO33632 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Rat, Mouse |
| Immunogen: | Recombinant Rat Vasopressin V1a receptor protein (7-52AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Avpr1a antibody at 2µg/ml + Mouse spleen tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 48 kDa Observed band size: 48 kDa . |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO33632 at dilution of 1:100. |
| Background: | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Involved in social memory formation. |
| Synonyms: | Vasopressin V1a receptor (V1aR) (AVPR V1a) (Antidiuretic hormone receptor 1a) (Vascular/hepatic-type arginine vasopressin receptor), Avpr1a |
| UniProt Protein Function: | AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1 Cellular Component: cytoplasmic vesicle membrane; integral to plasma membrane; integral to membrane; plasma membrane; cytoplasmic vesicle Molecular Function:V1A vasopressin receptor binding; peptide hormone binding; vasopressin receptor activity Biological Process: positive regulation of glutamate secretion; positive regulation of cellular pH reduction; positive regulation of systemic arterial blood pressure; cellular response to water deprivation; positive regulation of glycogen catabolic process; response to organic substance; elevation of cytosolic calcium ion concentration; positive regulation of cell proliferation; response to corticosterone stimulus; penile erection; positive regulation of prostaglandin biosynthetic process; grooming behavior; response to inorganic substance; maternal behavior; calcium-mediated signaling; myotube differentiation; positive regulation of heart rate; social behavior; positive regulation of cell growth; cellular response to hormone stimulus; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; negative regulation of transmission of nerve impulse; regulation of adrenocorticotropin hormone secretion; positive regulation of vasoconstriction; sperm ejaculation; positive regulation of blood pressure |
| NCBI Summary: | This gene encodes a receptor for arginine vasopressin, a neurohypophyseal hormone involved in diuresis inhibition, smooth muscle contraction, liver glycogenolysis stimulation and regulation of adrenocorticotropic hormone release from the pituitary. This receptor represents one of three G protein-coupled arginine vasopressin receptors which functions through a phosphotidylinositol-calcium second messenger system in vascular and hepatic tissues. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P30560 |
| NCBI GenInfo Identifier: | 108935913 |
| NCBI Gene ID: | 25107 |
| NCBI Accession: | P30560.4 |
| UniProt Secondary Accession: | P30560,Q5M8D1, Q62874, Q9QW18, |
| UniProt Related Accession: | P30560 |
| Molecular Weight: | 47,655 Da |
| NCBI Full Name: | Vasopressin V1a receptor |
| NCBI Synonym Full Names: | arginine vasopressin receptor 1A |
| NCBI Official Symbol: | Avpr1a  |
| NCBI Official Synonym Symbols: | V1a; AVPR; V1aRÂ Â |
| NCBI Protein Information: | vasopressin V1a receptor; antidiuretic hormone receptor 1a; arginine vasopressin receptor V1a; vascular/hepatic-type arginine vasopressin receptor |
| UniProt Protein Name: | Vasopressin V1a receptor |
| UniProt Synonym Protein Names: | AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor |
| Protein Family: | Vasopressin V1a receptor |
| UniProt Gene Name: | Avpr1a  |
| UniProt Entry Name: | V1AR_RAT |
| ELISA Kits |
| Rat AVPR V1a / Vasopressin V1a receptor ELISA Kit |
| Rat Vasopressin V1a receptor (Avpr1a) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Rat Vasopressin Vla Receptor (AVPR1A) ELISA Kit
Mouse Vasopressin V1a receptor (Avpr1a) ELISA Kit (MOEB2362)
Human Vasopressin V1a receptor (AVPR1A) ELISA Kit (HUEB2614)
