The AVL9 Antibody (PAC046914) is a polyclonal antibody developed for research involving AVL9, a protein associated with regulating cell division and cell growth. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the AVL9 protein, this antibody allows for the detection and analysis of AVL9 expression in various cell types, making it a valuable tool for studies in cell biology and cancer research.
AVL9 is a key player in the regulation of cell proliferation and is implicated in processes such as cell cycle progression and mitotic spindle assembly. Its role in controlling cell division makes it a promising target for research aimed at understanding cancer development and progression. By studying the function of AVL9, researchers can gain insight into potential therapeutic strategies for targeting aberrant cell growth in cancer and other diseases involving dysregulated cell division.
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO46914 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO46914 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Functions in cell migration.
Synonyms:
Late secretory pathway protein AVL9 homolog, AVL9, KIAA0241
UniProt Protein Function:
AVL9: Belongs to the AVL9 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 7p14.3Cellular Component: recycling endosomeBiological Process: cell migration
