ATG5 Rabbit Polyclonal Antibody (CAB11427)
- SKU:
- CAB11427
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | ATG5 Rabbit Polyclonal Antibody |
SKU: | CAB11427 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-275 of human ATG5 (NP_004840.1). |
Sequence: | TERE AEPY YLLL PRVS YLTL VTDK VKKH FQKV MRQE DISE IWFE YEGT PLKW HYPI GLLF DLLA SSSA LPWN ITVH FKSF PEKD LLHC PSKD AIEA HFMS CMKE ADAL KHKS QVIN EMQK KDHK QLWM GLQN DRFD QFWA INRK LMEY PAEE NGFR YIPF RIYQ TTTE RPFI QKLF RPVA ADGQ LHTL GDLL KEVC PSAI DPED GEKK NQVM IHGI EPML ETPL QWLS EHLS YPDN FLHI SIIP QPTD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE; ATG5 |
Positive Sample: | SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane. |
Calculated MW: | 32kDa |
Observed MW: | 55kDa |
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9474 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |