The Aurora Kinase C Polyclonal Antibody (CAB7930) is a valuable tool for researchers studying Aurora Kinase C, a key player in cell division and proliferation. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in a variety of applications, including Western blotting.Aurora Kinase C is a member of the Aurora kinase family, known for its role in regulating mitosis and chromosomal stability. By targeting Aurora Kinase C, researchers can gain insights into cell cycle regulation, mitotic spindle assembly, and chromosome segregation. This antibody enables the detection and analysis of Aurora Kinase C in different cell types, making it an essential tool for studies in cell biology, cancer research, and drug development.
The importance of Aurora Kinase C in cell division makes it a promising target for therapeutic interventions in cancer treatment. Understanding its function and regulation is crucial for developing targeted therapies that can disrupt the proliferation of cancer cells. The Aurora Kinase C Polyclonal Antibody is a valuable resource for researchers striving to unravel the complexities of cell cycle control and explore new avenues in cancer therapy.
Product Name:
AURKC Rabbit Polyclonal Antibody
SKU:
CAB7930
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human AURKC (NP_001015878.1).
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6795
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using AURKC Rabbit pAb (CAB7930) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
