The Aurora B Rabbit Monoclonal Antibody (CAB19539) is a high-quality antibody designed for research involving Aurora B, a key protein involved in cell division and regulation. This monoclonal antibody, produced in rabbits, is highly specific and sensitive for detecting Aurora B in human samples, with validation for use in various applications including Western blot and immunofluorescence.Aurora B is a member of the Aurora kinase family, playing a crucial role in ensuring proper chromosome segregation and cytokinesis during cell division. Dysregulation of Aurora B has been linked to tumorigenesis, making it an important target for cancer research. The Aurora B Rabbit Monoclonal Antibody enables accurate detection and analysis of Aurora B protein levels in different cell types, providing valuable insights into its function and potential therapeutic implications.
Researchers studying cell cycle regulation, cancer biology, and therapeutic targeting of cell division processes will find the Aurora B Rabbit Monoclonal Antibody to be a valuable tool in their investigations. Its high specificity and sensitivity make it ideal for studying the role of Aurora B in various cellular processes and diseases, ultimately contributing to advancements in treatment strategies for cancer and other related conditions.
Product Name:
Aurora B Rabbit Monoclonal Antibody
SKU:
CAB19539
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Aurora B (NP_004208.2).
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9212
Clone Number:
ARC50905
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Aurora B antibody (CAB19539) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
