The AURKB Polyclonal Antibody is a valuable tool for researchers studying the Aurora B kinase protein, a key player in cell division and chromosome segregation. This rabbit-derived antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By targeting the AURKB protein, researchers can gain insights into its functions and mechanisms in various cell types, providing valuable information for cancer research and other fields related to cell biology.
AURKB, also known as Aurora B, is essential for accurate cell division and ensuring genome stability. Dysregulation of Aurora B kinase has been implicated in various cancers and genetic disorders, making it a promising therapeutic target. By using the AURKB Polyclonal Antibody, researchers can unravel the complexities of Aurora B kinase activity and its role in disease processes, paving the way for the development of targeted therapies and treatments.
Product Name:
Aurora B Rabbit Polyclonal Antibody
SKU:
CAB1020
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Aurora B (NP_004208.2).
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9212
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Aurora B Rabbit pAb (CAB1020) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
