The ATXN2L Antibody (PACO02416) is a polyclonal antibody designed for research involving ATXN2L, a protein associated with neurodevelopmental disorders and motor neuron diseases. This antibody, generated in rabbits, shows high reactivity with ATXN2L in human samples and is validated for use in various applications, including Western blotting.ATXN2L, a member of the ataxin protein family, is known to play a role in RNA metabolism and may be involved in the pathogenesis of diseases like spinocerebellar ataxia. Research on ATXN2L could provide insights into the molecular mechanisms underlying these disorders, potentially leading to the development of new therapies or diagnostic tools.
With its ability to specifically bind to ATXN2L, this antibody is a valuable tool for studying the function and expression of ATXN2L in different cell types and tissues. Its versatility in applications makes it suitable for investigations in neurobiology, genetics, and neuroscience, offering researchers a reliable means to explore the role of ATXN2L in health and disease.
Antibody Name:
ATXN2L Antibody
Antibody SKU:
PACO02416
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Ataxin-2L.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ataxin-2L: an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]Protein type: RNA-binding; Membrane protein, peripheralChromosomal Location of Human Ortholog: 16p11Cellular Component: cytoplasm; membrane; nuclear speck; stress granuleMolecular Function: protein bindingBiological Process: stress granule assembly
UniProt Protein Details:
NCBI Summary:
This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
