The ATPB Rabbit Monoclonal Antibody is a valuable tool for researchers studying the ATPB protein, an essential component of the mitochondrial ATP synthase complex. This antibody, produced using rabbit-derived monoclonal technology, exhibits high specificity and sensitivity towards ATPB in a variety of experimental settings.ATPB, also known as ATP synthase subunit beta, plays a key role in ATP production through oxidative phosphorylation in the mitochondria. Dysregulation of ATPB expression or function can have profound effects on cellular energy metabolism, making it a crucial target for investigation in studies related to metabolism, aging, and various diseases.Validated for use in techniques such as immunohistochemistry and immunofluorescence, the ATPB Rabbit Monoclonal Antibody enables precise detection and visualization of ATPB localization within cells and tissues.
Its versatility and reliability make it an indispensable tool for exploring the molecular mechanisms underlying energy production and cellular function.Researchers in the fields of biochemistry, cell biology, and molecular biology can benefit from utilizing the ATPB Rabbit Monoclonal Antibody to enhance their understanding of ATPB's biological functions and its implications in health and disease. By utilizing this antibody, scientists can uncover valuable insights into the intricate workings of mitochondria and their role in maintaining cellular homeostasis.
Product Name:
ATPB Rabbit Monoclonal Antibody
SKU:
CAB11214
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 230-529 of human ATPB (NP_001677.2).
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core.
Purification Method:
Affinity purification
Gene ID:
506
Clone Number:
ARC53533
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ATPB Rabbit mAb (CAB11214) at1:20000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
