The ATPAF2 Polyclonal Antibody (CAB15928) is a valuable tool for researchers studying ATPAF2, a mitochondrial protein involved in ATP synthase assembly and function. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to ATPAF2, the antibody allows for the detection and analysis of this important protein in various cell types, making it ideal for studies in mitochondrial biology and energy metabolism.ATPAF2 is a key player in the assembly and activity of ATP synthase, the enzyme responsible for producing ATP in mitochondria. Dysregulation of ATPAF2 has been implicated in various diseases, including metabolic disorders and neurodegenerative conditions.
By studying ATPAF2 levels and function, researchers can gain valuable insights into the role of mitochondrial dysfunction in these pathologies and potentially identify new therapeutic targets for intervention.Overall, the ATPAF2 Polyclonal Antibody is a valuable asset for researchers investigating the role of ATPAF2 in cellular energy production and mitochondrial function. Its high specificity and reliability in Western blot applications make it an essential tool for unraveling the complexities of ATP synthase assembly and its impact on human health.
Product Name:
ATPAF2 Rabbit Polyclonal Antibody
SKU:
CAB15928
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 41-200 of human ATPAF2 (NP_663729.1).
This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 alpha subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. This gene is located within the Smith-Magenis syndrome region on chromosome 17. An alternatively spliced transcript variant has been described, but its biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
91647
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ATPAF2 Rabbit pAb (CAB15928) at 1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
