ATP7B Rabbit Polyclonal Antibody (CAB5676)
- SKU:
- CAB5676
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ATP7B Rabbit Polyclonal Antibody |
SKU: | CAB5676 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1251-1351 of human ATP7B (NP_001230111.1). |
Sequence: | SSVS VVLS SLQL KCYK KPDL ERYE AQAH GHMK PLTA SQVS VHIG MDDR WRDS PRAT PWDQ VSYV SQVS LSSL TSDK PSRH SAAA DDDG DKWS LLLN GRDE E |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | WD; PWD; WC1; WND; ATP7B |
Positive Sample: | Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Golgi apparatus, Golgi apparatus membrane, Mitochondrion, Multi-pass membrane protein, Multi-pass membrane protein, trans-Golgi network membrane. |
Calculated MW: | 157kDa |
Observed MW: | 157kDa |
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation.
Purification Method: | Affinity purification |
Gene ID: | 540 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |