ATP7A Rabbit Polyclonal Antibody (CAB8399)
- SKU:
- CAB8399
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ATP7A Rabbit Polyclonal Antibody |
SKU: | CAB8399 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-79 of human ATP7A (NP_000043.4). |
Sequence: | MDPS MGVN SVTI SVEG MTCN SCVW TIEQ QIGK VNGV HHIK VSLE EKNA TIIY DPKL QTPK TLQE AIDD MGFD AVIH NPD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MK; MNK; DSMAX; SMAX3; ATP7A |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Multi-pass membrane protein, Multi-pass membrane protein, cytosol, trans-Golgi network membrane. |
Calculated MW: | 163kDa |
Observed MW: | 163-200kDa |
This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.
Purification Method: | Affinity purification |
Gene ID: | 538 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |