ATP6V1G3 Rabbit Polyclonal Antibody (CAB14443)
- SKU:
- CAB14443
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | ATP6V1G3 Rabbit Polyclonal Antibody |
SKU: | CAB14443 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human ATP6V1G3 (NP_573569.1). |
Sequence: | MTSQ SQGI HQLL QAEK RAKD KLEE AKKR KGKR LKQA KEEA MVEI DQYR MQRD KEFR LKQS KIMG SQNN LSDE IEEQ TLGK IQEL NGHY NKYM ESVM NQLL SMVC DMKP EIHV NYRA TN |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | Vma10; ATP6G3; ATP6V1G3 |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, plasma membrane |
Calculated MW: | 14kDa |
Observed MW: | 14kDa |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 127124 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |