ATP6V1B2 Rabbit Polyclonal Antibody (CAB16771)
- SKU:
- CAB16771
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | ATP6V1B2 Rabbit Polyclonal Antibody |
SKU: | CAB16771 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 262-511 of human ATP6V1B2 (NP_001684.2). |
Sequence: | NLAN DPTI ERII TPRL ALTT AEFL AYQC EKHV LVIL TDMS SYAE ALRE VSAA REEV PGRR GFPG YMYT DLAT IYER AGRV EGRN GSIT QIPI LTMP NDDI THPI PDLT GYIT EGQI YVDR QLHN RQIY PPIN VLPS LSRL MKSA IGEG MTRK DHAD VSNQ LYAC YAIG KDVQ AMKA VVGE EALT SDDL LYLE FLQK FERN FIAQ GPYE NRTV FETL DIGW QLLR IFPK EMLK RIPQ STLS EFYP RDSA KH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | DOOD; HO57; VATB; VPP3; Vma2; ZLS2; ATP6B2; ATP6B1B2; ATP6V1B2 |
Positive Sample: | Mouse kidney,Mouse brain,Rat brain |
Cellular Localization: | Endomembrane system, Melanosome, Peripheral membrane protein. |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
Purification Method: | Affinity purification |
Gene ID: | 526 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |