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ATP6V1B2 Rabbit Polyclonal Antibody (CAB16771)

SKU:
CAB16771
Product Type:
Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
€139 - €419
Frequently bought together:

Description

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ATP6V1B2 Rabbit Polyclonal Antibody (CAB16771)

The ATP6V1B2 Polyclonal Antibody (CAB16771) is a valuable tool for researchers studying ATP6V1B2, a subunit of the ATPase enzyme complex involved in proton transport and acidification of intracellular compartments. This rabbit polyclonal antibody is highly specific to human samples and has been validated for use in Western blot applications.ATP6V1B2 plays a crucial role in maintaining cellular pH balance and intracellular transport processes. Dysregulation of ATP6V1B2 has been linked to various diseases, including cancer and metabolic disorders.

By using this antibody, researchers can detect and analyze ATP6V1B2 expression in different cell types, providing insights into its function and potential therapeutic applications.This ATP6V1B2 Polyclonal Antibody is a valuable tool for studying the mechanisms underlying ATP6V1B2 function and its involvement in disease processes. Its high specificity and reliability make it an ideal choice for researchers in the fields of cell biology, biochemistry, and molecular biology.

Product Name:ATP6V1B2 Rabbit Polyclonal Antibody
SKU:CAB16771
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 262-511 of human ATP6V1B2 (NP_001684.2).
Sequence:NLAN DPTI ERII TPRL ALTT AEFL AYQC EKHV LVIL TDMS SYAE ALRE VSAA REEV PGRR GFPG YMYT DLAT IYER AGRV EGRN GSIT QIPI LTMP NDDI THPI PDLT GYIT EGQI YVDR QLHN RQIY PPIN VLPS LSRL MKSA IGEG MTRK DHAD VSNQ LYAC YAIG KDVQ AMKA VVGE EALT SDDL LYLE FLQK FERN FIAQ GPYE NRTV FETL DIGW QLLR IFPK EMLK RIPQ STLS EFYP RDSA KH
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:DOOD; HO57; VATB; VPP3; Vma2; ZLS2; ATP6B2; ATP6B1B2; ATP6V1B2
Positive Sample:Mouse kidney,Mouse brain,Rat brain
Cellular Localization:Endomembrane system, Melanosome, Peripheral membrane protein.
Calculated MW:57kDa
Observed MW:57kDa

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.

Purification Method:Affinity purification
Gene ID:526
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using ATP6V1B2 Rabbit pAb (CAB16771) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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