ATP6V0C Rabbit Polyclonal Antibody (CAB16350)
- SKU:
- CAB16350
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | ATP6V0C Rabbit Polyclonal Antibody |
SKU: | CAB16350 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATP6V0C (NP_001185498.1). |
Sequence: | MSES KSGP EYAS FFAV MGAS AAMV FSAL GAAY GTAK SGTG IAAM SVMR PEQI MKSI IPVV MAGI IAIY GLVV AVLI ANSL NDDI SLYK SFLQ LGAG LSVG |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | ATPL; VATL; VPPC; Vma3; ATP6C; ATP6L; ATP6V0C |
Positive Sample: | Mouse kidney,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Multi-pass membrane protein, Vacuole membrane. |
Calculated MW: | 16kDa |
Observed MW: | 16kDa |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17.
Purification Method: | Affinity purification |
Gene ID: | 527 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |