ATP6V0C Monoclonal Antibody (CAB23757)
- SKU:
- CAB23757
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | ATP6V0C Monoclonal Antibody |
SKU: | CAB23757 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthesized peptide derived from human ATP6V0C. |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ATP6V0C; ATP6C; ATP6L; ATPL; VATL; VPPC; Vma3; ATPase H+ transporting V0 subunit c |
Positive Sample: | MCF7,293F |
Conjugate: | Unconjugated |
Cellular Localization: | Multi-pass membrane protein, Vacuole membrane. |
Calculated MW: | 15kDa |
Observed MW: | 16kDa |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17.
Purification Method: | Affinity purification |
Gene ID: | 527 |
Clone Number: | ARC61235 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |