UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components. V-ATPase is comprised of a membrane peripheral V(1) domain for ATP hydrolysis, and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is a component of the V(0) domain. Mutations in this gene are a cause of both cutis laxa type II and wrinkly skin syndrome. [provided by RefSeq, Jul 2009] |
UniProt Code: | Q9Y487 |
NCBI GenInfo Identifier: | 42741679 |
NCBI Gene ID: | 23545 |
NCBI Accession: | NP_036595 |
UniProt Secondary Accession: | Q9Y487 |
UniProt Related Accession: | Q9Y487 |
Molecular Weight: | |
NCBI Full Name: | V-type proton ATPase 116 kDa subunit a isoform 2 |
NCBI Synonym Full Names: | ATPase H+ transporting V0 subunit a2 |
NCBI Official Symbol: | ATP6V0A2Â Â |
NCBI Official Synonym Symbols: | A2; RTF; TJ6; WSS; ARCL; J6B7; STV1; TJ6M; TJ6S; VPH1; ARCL2A; ATP6A2; ATP6N1DÂ Â |
NCBI Protein Information: | V-type proton ATPase 116 kDa subunit a isoform 2; V-type proton ATPase 116 kDa subunit a |
UniProt Protein Name: | V-type proton ATPase 116 kDa subunit a isoform 2 |
UniProt Synonym Protein Names: | Lysosomal H(+)-transporting ATPase V0 subunit a2; TJ6; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2 |
Protein Family: | |
UniProt Gene Name: | ATP6V0A2Â Â |
UniProt Entry Name: | VPP2_HUMAN |