ATP6V0A1 Rabbit Polyclonal Antibody (CAB15258)
- SKU:
- CAB15258
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | ATP6V0A1 Rabbit Polyclonal Antibody |
SKU: | CAB15258 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-300 of human ATP6V0A1 (NP_001123493.1). |
Sequence: | EMDR KLRF VEKE IRKA NIPI MDTG ENPE VPFP RDMI DLEA NFEK IENE LKEI NTNQ EALK RNFL ELTE LKFI LRKT QQFF DEMA DPDL LEES SSLL EPSE MGRG TPLR LGFV AGVI NRER IPTF ERML WRVC RGNV FLRQ AEIE NPLE DPVT GDYV HKSV FIIF FQGD QLKN RVKK ICEG FRAS LYPC PETP QERK EMAS GVNT RIDD LQMV LNQT EDHR QRVL QAAA KNIR VWFI KVRK M |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | a1; Stv1; VPP1; Vph1; ATP6N1; DEE104; NEDEBA; ATP6N1A; ATP6V0A1 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic vesicle membrane, Melanosome, Multi-pass membrane protein. |
Calculated MW: | 96kDa |
Observed MW: | Refer to figures |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 535 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |