The ATP6AP1 Polyclonal Antibody (CAB1209) is a valuable tool for researchers studying ATP6AP1, a key protein involved in various cellular processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the ATP6AP1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in biochemistry and cell biology.ATP6AP1, also known as the accessory protein of vacuolar ATPase, plays a crucial role in maintaining cellular pH balance and regulating membrane trafficking. Its involvement in these essential functions underscores its importance in cellular physiology and pathology.
Researchers studying ATP6AP1 can gain valuable insights into processes such as endocytosis, autophagy, and lysosome function, which are critical for understanding various diseases, including neurodegenerative disorders and cancer.By providing a reliable tool for ATP6AP1 detection and analysis, the CAB1209 antibody facilitates cutting-edge research in molecular biology and biomedicine. Its high specificity and sensitivity make it an indispensable asset for scientists investigating the intricate mechanisms governed by the ATP6AP1 protein.
Product Name:
ATP6AP1 Rabbit Polyclonal Antibody
SKU:
CAB1209
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-390 of human ATP6AP1 (NP_001174.2).
This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development.
Purification Method:
Affinity purification
Gene ID:
537
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using ATP6AP1 Rabbit pAb (CAB1209) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
