ATP5S Antibody (PACO22166)
- SKU:
- PACO22166
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
ATP5S Antibody (PACO22166)
The ATP5S Polyclonal Antibody (PACO22166) is a valuable tool for researchers studying ATP5S, a subunit of mitochondrial ATP synthase that plays a key role in energy production within cells. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the ATP5S protein, this antibody enables precise detection and analysis in a variety of cell types, making it essential for studies in biochemistry and cell biology.ATP5S is essential for the synthesis of ATP, the primary energy source for cellular functions.
Dysfunction in ATP5S has been linked to various diseases, including mitochondrial disorders and metabolic diseases. By understanding the role of ATP5S in cellular energy production, researchers can develop targeted therapies for these conditions and potentially improve patient outcomes. The ATP5S Polyclonal Antibody is a reliable tool for exploring the functions and mechanisms of ATP5S in health and disease.
| Antibody Name: | ATP5S Antibody (PACO22166) |
| Antibody SKU: | PACO22166 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human ATP5S. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HT-29 cells, using ATP5S antibody. |
| Background: | Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H+ conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway By similarity. |
| Synonyms: | ATP synthase subunit s; mitochondrial [Precursor]; ATP synthase-coupling factor B; Mitochondrial ATP synthase regulatory component factor B; ATP5S |
| UniProt Protein Function: | ATP5S: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway. Belongs to the ATP synthase subunit s family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: MitochondrialChromosomal Location of Human Ortholog: 14q21.3Cellular Component: proton-transporting ATP synthase complex, coupling factor F(o); mitochondrial inner membraneMolecular Function: metal ion binding; hydrogen ion transmembrane transporter activityBiological Process: cellular metabolic process; proton transport; mitochondrial ATP synthesis coupled proton transport |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99766 |
| NCBI GenInfo Identifier: | 51558777 |
| NCBI Gene ID: | 27109 |
| NCBI Accession: | NP_001003805.1 |
| UniProt Secondary Accession: | Q99766,Q8WWX3, Q96F77, A8K1U3, D9N156 |
| UniProt Related Accession: | Q99766 |
| Molecular Weight: | 14,667 Da |
| NCBI Full Name: | ATP synthase subunit s, mitochondrial isoform b |
| NCBI Synonym Full Names: | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) |
| NCBI Official Symbol: | ATP5SÂ Â |
| NCBI Official Synonym Symbols: | FB; ATPW; HSU79253Â Â |
| NCBI Protein Information: | ATP synthase subunit s, mitochondrial; ATP synthase-coupling factor B; ATP synthase coupling factor B-like 1; ATP synthase coupling factor B, mitochondrial; mitochondrial ATP synthase regulatory component factor B; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B) |
| UniProt Protein Name: | ATP synthase subunit s, mitochondrial |
| UniProt Synonym Protein Names: | ATP synthase-coupling factor B; FB; Mitochondrial ATP synthase regulatory component factor B |
| Protein Family: | ATP synthase |
| UniProt Gene Name: | ATP5SÂ Â |
| UniProt Entry Name: | ATP5S_HUMAN |
| Antibodies |
| ATP5S Antibody (PACO00443) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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