The ATP5L2 Antibody (PACO03857) is a valuable tool for researchers studying the ATP5L2 protein, a key component of the mitochondrial ATP synthase complex. This polyclonal antibody, produced in rabbits, has been tested and validated for use in Western blot applications with human samples. By specifically binding to the ATP5L2 protein, this antibody allows for accurate detection and analysis in various cell types.ATP5L2 is involved in cellular energy production through the generation of ATP, making it essential for a wide range of biological processes.
Dysregulation of ATP5L2 has been linked to diseases such as mitochondrial disorders, metabolic diseases, and cancer. Research into the function and regulation of ATP5L2 is vital for understanding these conditions and developing targeted therapies.With its high reactivity and specificity, the ATP5L2 Antibody is a valuable tool for scientists investigating the role of ATP5L2 in health and disease. Its use in immunology, metabolism, and cancer research makes it a versatile option for studying the biological functions of the ATP5L2 protein.
Antibody Name:
ATP5L2 Antibody
Antibody SKU:
PACO03857
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human ATP5L2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ATP5L2; ATP5K2; ATP synthase subunit g 2; mitochondrial; ATPase subunit g 2
UniProt Protein Function:
ATP5L2: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. Belongs to the ATPase g subunit family.Chromosomal Location of Human Ortholog: 22q13.2Cellular Component: mitochondrion
