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ATP5J2 Rabbit Polyclonal Antibody (CAB17055)

SKU:
CAB17055
Product Type:
Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
€139 - €419
Frequently bought together:

Description

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ATP5J2 Rabbit Polyclonal Antibody (CAB17055)

The ATP5J2 Polyclonal Antibody (CAB17055) is a powerful tool for researchers studying ATP5J2, a key subunit of the mitochondrial ATP synthase complex involved in energy production. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications. By binding specifically to ATP5J2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in molecular biology and bioenergetics.

ATP5J2 is essential for ATP synthesis, the primary source of energy in cells. Dysfunction in ATP production can lead to various diseases including metabolic disorders and neurodegenerative conditions. By studying the role of ATP5J2, researchers can gain valuable insights into cellular bioenergetics and potential therapeutic targets for diseases related to mitochondrial dysfunction. The ATP5J2 Polyclonal Antibody is a valuable tool for advancing research in this important field.

Product Name:ATP5J2 Rabbit Polyclonal Antibody
SKU:CAB17055
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-94 of human ATP5J2 (NP_004880.1).
Sequence:MASV GECP APVP VKDK KLLE VKLG ELPS WILM RDFS PSGI FGAF QRGY YRYY NKYI NVKK GSIS GITM VLAC YVLF SYSF SYKH LKHE RLRK YH
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:ATP5J2; ATP5JL
Positive Sample:Mouse brain,Mouse kidney,Rat heart
Cellular Localization:mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrion, nuclear membrane
Calculated MW:11kDa
Observed MW:11kDa

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The catalytic portion of mitochondrial ATP synthase consists of five different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the f subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. This gene has multiple pseudogenes. Naturally occurring read-through transcription also exists between this gene and the downstream pentatricopeptide repeat domain 1 (PTCD1) gene.

Purification Method:Affinity purification
Gene ID:9551
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ATP5J2 Rabbit pAb (CAB17055) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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