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ATP5H Rabbit Polyclonal Antibody (CAB4425)

SKU:
CAB4425
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ATP5H
ATPQ
  • Signal Transduction Antibodies 2 Anti-ATP5H Antibody CAB4425
  • Signal Transduction Antibodies 2 Anti-ATP5H Antibody CAB4425
  • Signal Transduction Antibodies 2 Anti-ATP5H Antibody CAB4425
  • Signal Transduction Antibodies 2 Anti-ATP5H Antibody CAB4425
  • Signal Transduction Antibodies 2 Anti-ATP5H Antibody CAB4425
€139 - €419
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Description

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ATP5H Rabbit Polyclonal Antibody (CAB4425)

The ATP5H Polyclonal Antibody (CAB4425) is a valuable tool for researchers studying ATP5H, a subunit of ATP synthase that plays a vital role in cellular energy production. This antibody is raised in rabbits and is highly specific to human samples, making it ideal for experiments involving ATP5H detection and analysis.ATP5H is a key component of the mitochondrial ATP synthase complex, responsible for generating ATP, the energy currency of the cell. Dysfunction in ATP5H has been linked to various human diseases, including mitochondrial disorders and metabolic syndromes.

By targeting ATP5H with this antibody, researchers can gain insights into its function and potential implications in health and disease.With its validated use in Western blot applications, the ATP5H Polyclonal Antibody offers reliable results for studies in biochemistry, cell biology, and mitochondrial research. Its high reactivity and specificity make it a valuable asset for scientists investigating the role of ATP5H in cellular metabolism and energy regulation.

Product Name:ATP5H Rabbit Polyclonal Antibody
SKU:CAB4425
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human ATP5H (NP_006347.1).
Sequence:MAGR KLAL KTID WVAF AEII PQNQ KAIA SSLK SWNE TLTS RLAA LPEN PPAI DWAY YKAN VAKA GLVD DFEK KFNA LKVP VPED KYTA QVDA EEKE DVKS CAEW VSLS KARI VEYE KEME KMKN LIPF DQMT IEDL NEAF PETK LDKK KYPY WPHQ PIEN L
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:ATPQ; APT5H; ATP5H
Positive Sample:COS-7,HepG2,U-251MG,BxPC-3,HeLa,Mouse kidney,Mouse thymus,Mouse brain,Rat spinal cord
Conjugate:Unconjugated
Cellular Localization:Mitochondrion, Mitochondrion inner membrane.
Calculated MW:18kDa
Observed MW:18kDa

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15.

Purification Method:Affinity purification
Gene ID:10476
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ATP5H Rabbit pAb (CAB4425) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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