The ATP5A1 Rabbit Monoclonal Antibody is a powerful tool for researchers studying ATP5A1, a key subunit of the mitochondrial F1F0-ATP synthase complex involved in cellular energy production. This high-quality antibody, produced in rabbits, is highly specific for human samples and is validated for use in a variety of applications, including Western blotting and immunohistochemistry.By targeting the ATP5A1 protein, this antibody allows for the detection and analysis of ATP5A1 in different cell types, making it ideal for research in cell biology, metabolism, and bioenergetics.
Understanding the function and regulation of ATP5A1 is essential for unraveling the complexities of energy metabolism and mitochondrial dysfunction, which are implicated in various diseases such as cancer, neurodegenerative disorders, and metabolic syndromes.The ATP5A1 Rabbit Monoclonal Antibody is a valuable tool for researchers seeking to unravel the role of ATP5A1 in cellular physiology and disease pathology, ultimately paving the way for the development of novel therapeutic strategies targeting mitochondrial function.
Product Name:
ATP5A1 Rabbit Monoclonal Antibody
SKU:
CAB11217
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ATP5A1 (P25705).
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16.
Purification Method:
Affinity purification
Gene ID:
498
Clone Number:
ARC0549
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ATP5A1 Rabbit mAb (CAB11217) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
