ATP23 Rabbit Polyclonal Antibody (CAB12885)
- SKU:
- CAB12885
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ATP23 Rabbit Polyclonal Antibody |
SKU: | CAB12885 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_150592.1). |
Sequence: | MAGA PDER RRGP AAGE QLQQ QHVS CQVF PERL AQGN PQQG FFSS FFTS NQKC QLRL LKTL ETNP YVKL LLDA MKHS GCAV NKDR HFSC EDCN GNVS GGFD ASTS QIVL CQNN IHNQ AHMN RVVT HELI HAFD HCRA HVDW FTNI RHLA CSEV RAAN LSGD CSLV NEIF RLHF GLKQ HHQT CVRD RATL SILA VRNI SKEV AKKA VDEV FESC FNDH EPFG RIPH NKTY ARYA HRDF ENRD RYYS NI |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:3000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | KUB3; XRCC6BP1; ATP23 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extrinsic component of mitochondrial inner membrane, plasma membrane |
Calculated MW: | 28kDa |
Observed MW: | 28kDa |
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 91419 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |