The ATP1A3 Polyclonal Antibody (CAB16036) is a specialized research tool designed for studying ATP1A3, a crucial protein involved in the function of ion pumps in cells. This antibody, produced in rabbits, is highly sensitive and specific for detecting ATP1A3 in human samples, making it ideal for a variety of research applications such as Western blot analysis.ATP1A3 is a key component of the sodium-potassium pump, essential for maintaining the electrochemical gradient across cell membranes. Dysregulation of ATP1A3 has been linked to a variety of neurological disorders, making it a hot topic for research in neuroscience and neurology.
By utilizing the ATP1A3 Polyclonal Antibody, researchers can pinpoint the expression and localization of ATP1A3 in different cell types, providing valuable insights into its function and potential therapeutic targets.Understanding the role of ATP1A3 in cellular processes is crucial for advancing our knowledge of neurological diseases and developing targeted treatments. The ATP1A3 Polyclonal Antibody is a valuable tool for researchers seeking to unravel the complexities of ATP1A3 biology and its implications in health and disease.
Product Name:
ATP1A3 Rabbit Polyclonal Antibody
SKU:
CAB16036
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human ATP1A3 (NP_689509.1).
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
478
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ATP1A3 Rabbit pAb (CAB16036) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
