Na+/K+-ATPase Rabbit Polyclonal Antibody (CAB7878)
- SKU:
- CAB7878
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | Na+/K+-ATPase Rabbit Polyclonal Antibody |
SKU: | CAB7878 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Na+/K+-ATPase (NP_000692.2). |
Sequence: | MGKG VGRD KYEP AAVS EQGD KKGK KGKK DRDM DELK KEVS MDDH KLSL DELH RKYG TDLS RGLT SARA AEIL ARDG PNAL TPPP TTPE WIKF CRQL FGGF |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CMT2DD; HOMGSMR2; Na+/K+-ATPase |
Positive Sample: | HeLa,HeLa membrane protein,C2C12,C6 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Melanosome, Multi-pass membrane protein. |
Calculated MW: | 113kDa |
Observed MW: | 100kDa |
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 476 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |