Atp1a1 (Ab-23) Antibody (PACO23621)
- SKU:
- PACO23621
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | Atp1a1 (Ab-23) Antibody (PACO23621) |
| Antibody SKU: | PACO23621 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IF:1:100-1:500 |
| Species Reactivity: | Human, Rat |
| Immunogen: | Synthesized non-phosphopeptide derived from human ATP1 alpha 1/Na+K+ ATPase1 around the phosphorylation site of serine 23 (K-K-S(p)-K-K). |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence analysis of HeLa cells, using ATP1alpha 1/Na+K+ ATPase1 (Ab-23) antibody. |
 | Western blot analysis of extracts from K562 cells (Lane 2), using ATP1 alpha 1/Na+K+ ATPase1 (Ab-23) antiobdy. The lane on the left is treated with synthesized peptide. |
 | Western blot analysis of extracts from HeLa cells, using ATP1 alpha 1/Na+K+ ATPase1 (Ab-23) antibody. |
| Background: | This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. |
| Synonyms: | A1A1; AT1A1; ATPase; Na+/K+ transporting; alpha 1 polypeptide |
| UniProt Protein Function: | This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. |
| UniProt Protein Details: | |
| NCBI Summary: | mediates Na+ and K+ transport; may play a role in regulation of blood pressure [RGD, Feb 2006] |
| UniProt Code: | P06685 |
| NCBI GenInfo Identifier: | 114376 |
| NCBI Gene ID: | 24211 |
| NCBI Accession: | P06685.1 |
| UniProt Secondary Accession: | P06685,Q64609 |
| UniProt Related Accession: | P06685 |
| Molecular Weight: | 113,054 Da |
| NCBI Full Name: | Sodium/potassium-transporting ATPase subunit alpha-1 |
| NCBI Synonym Full Names: | ATPase Na+/K+ transporting subunit alpha 1 |
| NCBI Official Symbol: | Atp1a1Â Â |
| NCBI Official Synonym Symbols: | Nkaa1b  |
| NCBI Protein Information: | sodium/potassium-transporting ATPase subunit alpha-1 |
| UniProt Protein Name: | Sodium/potassium-transporting ATPase subunit alpha-1 |
| UniProt Synonym Protein Names: | Sodium pump subunit alpha-1 |
| Protein Family: | Sodium/potassium-transporting ATPase |
| UniProt Gene Name: | Atp1a1Â Â |
| UniProt Entry Name: | AT1A1_RAT |
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