The ATP11C Polyclonal Antibody (CAB16616) is a valuable tool for researchers studying ATP11C, a P-type ATPase involved in translocating phospholipids across membranes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding to the ATP11C protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for investigations in cell biology and lipid transport.ATP11C plays a crucial role in maintaining membrane asymmetry, which is essential for various cellular processes such as vesicle trafficking and signal transduction.
Dysregulation of ATP11C has been implicated in disorders related to lipid metabolism and membrane integrity. Therefore, studying ATP11C function is critical for understanding its contribution to human health and disease.Researchers interested in lipid transport, membrane dynamics, and cellular signaling pathways will find the ATP11C Polyclonal Antibody (CAB16616) to be a valuable asset in their experimental work. Its specificity and reliability make it a trusted reagent for investigating the role of ATP11C in cellular physiology and disease mechanisms.
Product Name:
ATP11C Rabbit Polyclonal Antibody
SKU:
CAB16616
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 430-650 of human ATP11C (NP_775965.2).
Enables phosphatidylethanolamine flippase activity and phosphatidylserine flippase activity. Predicted to be involved in phospholipid translocation; positive regulation of B cell differentiation; and pre-B cell differentiation. Located in endoplasmic reticulum and plasma membrane. Is integral component of plasma membrane. Implicated in X-linked congenital hemolytic anemia.
Purification Method:
Affinity purification
Gene ID:
286410
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ATP11C Rabbit pAb (CAB16616) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
