The ATOH7 Polyclonal Antibody (CAB7273) is a valuable tool for researchers studying the ATOH7 protein, also known as Math5, which plays a crucial role in the development of retinal ganglion cells. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.ATOH7 is a key transcription factor involved in the differentiation of retinal ganglion cells, which are essential for transmitting visual information from the eye to the brain.
Dysregulation of ATOH7 has been implicated in various retinal disorders, making it an important target for research in ophthalmology and vision science.By using the ATOH7 Polyclonal Antibody, researchers can detect and analyze the expression of ATOH7 in different cell types and tissues, providing valuable insights into its role in retinal development and disease pathology. This antibody is essential for advancing our understanding of ATOH7 and its potential therapeutic implications in the treatment of retinal disorders.
Product Name:
ATOH7 Rabbit Polyclonal Antibody
SKU:
CAB7273
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 47-152 of human ATOH7 (NP_660161.1).
This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment.
Purification Method:
Affinity purification
Gene ID:
220202
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of A-549 cells using ATOH7 Rabbit pAb (CAB7273).Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution.
