The ATOH1 Polyclonal Antibody (CAB6530) is a valuable tool for researchers studying the ATOH1 protein, a transcription factor involved in the development of sensory organs, particularly the inner ear and hair cells. This antibody, produced through rabbit immunization, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ATOH1 protein, this antibody enables precise detection and analysis in various cell types, making it an essential component for studies in developmental biology and sensory organ regeneration.
ATOH1 is a key player in the differentiation and maturation of sensory cells, making it a crucial target for research into hearing loss, balance disorders, and other sensory-related conditions. By understanding the role of ATOH1 in cellular development and regeneration, researchers can potentially uncover new therapeutic approaches for treating these disorders and improving sensory function. The ATOH1 Polyclonal Antibody provides researchers with a reliable tool to further investigate the mechanisms underlying sensory organ development and regeneration.
Product Name:
ATOH1 Rabbit Polyclonal Antibody
SKU:
CAB6530
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 215-354 of human ATOH1 (NP_005163.1).
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in neuron differentiation; positive regulation of neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including generation of neurons; inner ear morphogenesis; and positive regulation of inner ear auditory receptor cell differentiation. Predicted to be part of chromatin. Predicted to be active in nucleus.
Purification Method:
Affinity purification
Gene ID:
474
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ATOH1 Antibody (CAB6530) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
