ATL1 Rabbit Polyclonal Antibody (CAB5302)
- SKU:
- CAB5302
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ATL1 Rabbit Polyclonal Antibody |
SKU: | CAB5302 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ATL1 (NP_056999.2). |
Sequence: | MAKN RRDR NSWG GFSE KTYE WSSE EEEP VKKA GPVQ VLIV KDDH SFEL DETA LNRI LLSE AVRD KEVV AVSV AGAF RKGK SFLM DFML RYMY NQES VDWV GDYN EPLT GFSW RGGS ERET TGIQ IWSE IFLI NKPD GKKV AVLL MDTQ GTFD SQST LRDS ATVF ALST MISS IQVY NLSQ NVQE DDLQ HLQL FTEY GRLA MEET FLKP FQSL IFLV RDWS FPYE FSYG ADGG AKFL EKRL KVSG NQHE ELQN VRKH IHSC FTNI SCFL LPHP GLKV ATNP |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | FSP1; GBP3; SPG3; HSN1D; SPG3A; AD-FSP; atlastin1; ATL1 |
Positive Sample: | SH-SY5Y,LOVO,H460,293T,U-87MG,U-251MG,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Endoplasmic reticulum membrane, Golgi apparatus membrane, Multi-pass membrane protein, axon. |
Calculated MW: | 64kDa |
Observed MW: | 64kDa |
The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 51062 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |