ATIC Rabbit Polyclonal Antibody (CAB5559)
- SKU:
- CAB5559
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ATIC Rabbit Polyclonal Antibody |
SKU: | CAB5559 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ATIC (NP_004035.2). |
Sequence: | MAPG QLAL FSVS DKTG LVEF ARNL TALG LNLV ASGG TAKA LRDA GLAV RDVS ELTG FPEM LGGR VKTL HPAV HAGI LARN IPED NADM ARLD FNLI RVVA CNLY PFVK TVAS PGVT VEEA VEQI DIGG VTLL RAAA KNHA RVTV VCEP EDYV VVST EMQS SESK DTSL ETRR QLAL KAFT HTAQ YDEA ISDY FRKQ YSKG VSQM PLRY GMNP HQTP AQLY TLQP KLPI TVLN GAPG FINL CDAL NAWQ LVKE LKEA LGIP AAAS FKHV SPAG AAVG IPLS EDEA KVCM VYDL YKTL TPIS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PURH; AICAR; AICARFT; IMPCHASE; HEL-S-70p; ATIC |
Positive Sample: | MCF7,SW480,NCI-H460,HepG2,SW620,HT-29,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extracellular exosome, plasma membrane |
Calculated MW: | 65kDa |
Observed MW: | 62kDa |
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
Purification Method: | Affinity purification |
Gene ID: | 471 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |