The ATG9B Polyclonal Antibody (CAB7406) is a vital tool for researchers studying autophagy processes and cellular trafficking. This antibody, produced in rabbits, specifically targets the ATG9B protein, a key player in the autophagy pathway.ATG9B is involved in the formation and maintenance of autophagosomes, which are responsible for degrading and recycling cellular components. Dysfunction in autophagy has been linked to various diseases, including neurodegenerative disorders and cancer. By targeting ATG9B with this antibody, researchers can visualize and analyze the protein's localization and expression levels in different cell types.
Validated for use in Western blot applications, the ATG9B Polyclonal Antibody allows for precise detection and quantification of ATG9B protein levels. Its high reactivity with human samples makes it suitable for a wide range of studies in cell biology, cancer research, and disease modeling.Understanding the role of ATG9B in autophagy regulation is essential for developing new therapeutic strategies targeting this pathway. With the ATG9B Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying autophagy and its implications for human health.
Product Name:
ATG9B Rabbit Polyclonal Antibody
SKU:
CAB7406
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 715-924 of human ATG9B (NP_001303985.1).
This gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
285973
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of HUH-7 cells, using ATG9B antibody (CAB7406) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
