ATG7 Rabbit Monoclonal Antibody (CAB19604)
- SKU:
- CAB19604
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | ATG7 Rabbit Monoclonal Antibody |
SKU: | CAB19604 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Atg7(Apg7) (O95352). |
Sequence: | MAAA TGDP GLSK LQFA PFSS ALDV GFWH ELTQ KKLN EYRL DEAP KDIK GYYY NGDS AGLP ARLT LEFS AFDM SAPT PARC CPAI GTLY NTNT LESF KTAD |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | GSA7; [KD Validated] ATG7 |
Positive Sample: | HeLa,THP-1,293T,Mouse brain,Mouse lung,Mouse spleen,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Preautophagosomal structure. |
Calculated MW: | 78kDa |
Observed MW: | 77kDa |
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 10533 |
Clone Number: | ARC0083 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |