ATG7 Rabbit Polyclonal Antibody (CAB7360)
- SKU:
- CAB7360
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | ATG7 Rabbit Polyclonal Antibody |
SKU: | CAB7360 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-676 of human ATG7 (NP_001129503.2). |
Sequence: | LGFD TFVV MRHG LKKP KQQG AGDL CPNH PVAS ADLL GSSL FANI PGYK LGCY FCND VVAP GDST RDRT LDQQ CTVS RPGL AVIA GALA VELM VSVL QHPE GGYA IASS SDDR MNEP PTSL GLVP HQVL DQYE REGF NFLA KVFN SSHS FLED LTGL TLLH QETQ AAEI WDMS DDET I |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:100 |
Synonyms: | GSA7; APG7L; SCAR31; APG7-LIKE; ATG7 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Preautophagosomal structure. |
Calculated MW: | 78kDa |
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 10533 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |