ATG4D Rabbit Polyclonal Antibody (CAB7842)
- SKU:
- CAB7842
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
Product Name: | ATG4D Rabbit Polyclonal Antibody |
SKU: | CAB7842 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 265-474 of human ATG4D (NP_116274.3). |
Sequence: | DVTR LVVY VSQD CTVY KADV ARLV ARPD PTAE WKSV VILV PVRL GGET LNPV YVPC VKEL LRCE LCLG IMGG KPRH SLYF IGYQ DDFL LYLD PHYC QPTV DVSQ ADFP LESF HCTS PRKM AFAK MDPS CTVG FYAG DRKE FETL CSEL TRVL SSSS ATER YPMF TLAE GHAQ DHSL DDLC SQLA QPTL RLPR TGRL LRAK RPSS EDFV FL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | APG4D; AUTL4; APG4-D; HsAPG4D; ATG4D |
Positive Sample: | Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion matrix. |
Calculated MW: | 53kDa |
Observed MW: | 53kDa |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 84971 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |