ATG4B Rabbit Polyclonal Antibody (CAB2837)
- SKU:
- CAB2837
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | ATG4B Rabbit Polyclonal Antibody |
SKU: | CAB2837 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 1-393 of human ATG4B (NP_037457.3). |
Sequence: | MDAA TLTY DTLR FAEF EDFP ETSE PVWI LGRK YSIF TEKD EILS DVAS RLWF TYRK NFPA IGGT GPTS DTGW GCML RCGQ MIFA QALV CRHL GRDW RWTQ RKRQ PDSY FSVL NAFI DRKD SYYS IHQI AQMG VGEG KSIG QWYG PNTV AQVL KKLA VFDT WSSL AVHI AMDN TVVM EEIR RLCR TSVP CAGA TAFP ADSD RHCN GFPA GAEV TNRP SPWR PLVL LIPL RLGL TDIN EAYV ETLK HCFM MPQS LGVI GGKP NSAH YFIG YVGE ELIY LDPH TTQP AVEP TDGC FIPD ESFH CQHP PCRM SIAE LDPS IAVG FFCK TEDD FNDW CQQV KKLS LLGG ALPM FELV ELQP SHLA CPDV LNLS LDSS DVER LERF FDSE DEDF EILS L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | APG4B; AUTL1; HsAPG4B; ATG4B |
Positive Sample: | RD |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 44kDa |
Observed MW: | 48kDa |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 23192 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |