The ATG3 Rabbit Monoclonal Antibody (CAB19594) is a cutting-edge tool for researchers studying ATG3, a key player in the autophagy process essential for cellular homeostasis and survival. This highly specific antibody, generated from rabbit immunizations, is optimized for detecting and analyzing ATG3 protein levels in a variety of samples, but is particularly effective in human samples.ATG3 is a crucial component of the autophagy pathway, responsible for conjugating ATG8-like proteins to phosphatidylethanolamine, facilitating the formation of autophagosomes. Dysregulation of autophagy has been implicated in various diseases, including neurodegenerative disorders, cancer, and infectious diseases.
Therefore, the ATG3 Rabbit Monoclonal Antibody is an invaluable tool for researchers investigating the role of autophagy in these pathological conditions.Validated for use in Western blot applications, this antibody provides reliable and reproducible results, enabling precise analysis of ATG3 expression levels in different cell types and experimental conditions. With its high specificity and sensitivity, the ATG3 Rabbit Monoclonal Antibody is an essential asset for immunology, cancer, and autophagy research.
Product Name:
ATG3 Rabbit Monoclonal Antibody
SKU:
CAB19594
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Apg3 (Atg3) (Q9NT62).
This gene encodes a ubiquitin-like-conjugating enzyme and is a component of ubiquitination-like systems involved in autophagy, the process of degradation, turnover and recycling of cytoplasmic constituents in eukaryotic cells. This protein is known to play a role in regulation of autophagy during cell death. A pseudogene of this gene is located on chromosome 20. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
64422
Clone Number:
ARC0073
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ATG3 antibody (CAB19594) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 40s.
