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ATG3 Monoclonal Antibody [PAT15F6AT] (CPAB0613)

SKU:
CPAB0613
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1 k
Clone:
PAT15F6AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

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ATG3 Monoclonal Antibody [PAT15F6AT] (CPAB0613)

The ATG3 Polyclonal Antibody (CPAB0613) is a powerful tool for research involving the ATG3 protein, a key player in the process of autophagy. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications. By specifically binding to the ATG3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable asset for studies in cell biology and disease mechanisms.ATG3 is an essential component of the autophagy pathway, responsible for facilitating the conjugation of ATG8 to phosphatidylethanolamine during autophagosome formation.

Dysregulation of autophagy has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic conditions. Research on ATG3 and its role in autophagy regulation is crucial for understanding the underlying mechanisms of these diseases and developing targeted therapies.With its high specificity and sensitivity, the ATG3 Polyclonal Antibody (CPAB0613) offers researchers a reliable tool for studying the intricate process of autophagy and its implications in health and disease. Invest in this antibody to enhance your research efforts and advance our understanding of autophagy biology.

Product Name:ATG3 Antibody
Product Sku:CPAB0613
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ATG3mAb, clone PAT15F6AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ATG3 protein (1-314 amino acids purified from Ecoli.
Clone:PAT15F6AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:ATG3 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1 k
Background:Autophagy Related 3 (ATG3) is a conjugating enzyme essential for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. ATG3 is localizes to the cytoplasm and is expressed in tissues with predominant levels found in kidney, placenta, liver, heart and skeletal muscle. ATG3 catalyzes a reaction which is necessary for autophagy. That reaction is the formation of the Atg8-phosphatidylethanolamine (ATG-PE) conjugate.
Synonyms:APG3, APG3-LIKE, APG3L, PC3-96, Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, hApg3, PC3-96, ATG3.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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