The ATG2B Polyclonal Antibody (CAB8498) is a valuable tool for researchers studying ATG2B, a protein involved in autophagy and intracellular membrane trafficking processes. This antibody, generated in rabbits, shows high specificity and sensitivity in detecting ATG2B in human samples, making it suitable for use in Western blot applications.ATG2B is a key player in the autophagy pathway, a cellular process responsible for degrading and recycling damaged or unnecessary cellular components. Dysregulation of autophagy has been implicated in various diseases, including neurodegenerative disorders, cancer, and metabolic syndromes.
By targeting ATG2B, researchers can gain insights into the mechanisms underlying these pathologies and develop novel therapeutic strategies.The ATG2B Polyclonal Antibody allows for precise detection and quantification of ATG2B protein levels in different cell types and tissues, facilitating research in autophagy-related processes and diseases. Its reliability and reproducibility make it an essential tool for scientists studying cellular homeostasis, organelle dynamics, and the interplay between autophagy and disease progression.
Product Name:
ATG2B Rabbit Polyclonal Antibody
SKU:
CAB8498
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1360-1600 of human ATG2B (NP_060506.5).
This gene encodes a protein required for autophagy. The encoded protein is involved in autophagosome formation. A germline duplication of a region that includes this gene is associated with predisposition to myeloid malignancies.
Purification Method:
Affinity purification
Gene ID:
55102
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ATG2B antibody (CAB8498) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
