The ATG2A Polyclonal Antibody (CAB8576) is specifically designed for research involving ATG2A, a protein involved in autophagy, a crucial cellular process for maintaining homeostasis and cell survival. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to ATG2A, this antibody enables precise detection and analysis of ATG2A protein levels in various cell types, making it an ideal tool for studies in autophagy, cell biology, and disease research.ATG2A is a key player in the autophagy process, responsible for mediating the formation of autophagosomes and guiding the sequestration of cellular components for degradation.
Dysregulation of autophagy, including ATG2A dysfunction, has been linked to various diseases such as neurodegenerative disorders, cancer, and metabolic conditions. Therefore, investigating the role of ATG2A in autophagy regulation is essential for understanding the pathogenesis of these diseases and developing targeted therapies aimed at restoring proper cellular function.
Product Name:
ATG2A Rabbit Polyclonal Antibody
SKU:
CAB8576
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human ATG2A (NP_055919.2).
Predicted to enable phosphatidylinositol-3-phosphate binding activity. Involved in autophagosome assembly. Predicted to be located in endoplasmic reticulum membrane; lipid droplet; and phagophore assembly site membrane. Predicted to be active in phagophore assembly site. Predicted to be extrinsic component of membrane.
Purification Method:
Affinity purification
Gene ID:
23130
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ATG2A Antibody (CAB8576) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
