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ATG16L1 Rabbit Monoclonal Antibody (CAB3637)

SKU:
CAB3637
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Autophagy
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ATG16L1 Rabbit Monoclonal Antibody
SKU:CAB3637
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 6-105 of human ATG16L1 (Q676U5).
Sequence:RAAD FPRW KRHI SEQL RRRD RLQR QAFE EIIL QYNK LLEK SDLH SVLA QKLQ AEKH DVPN RHEI SPGH DGTW NDNQ LQEM AQLR IKHQ EELT ELHK KRGE
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:IBD10; WDR30; APG16L; ATG16A; ATG16L; ATG16L1
Positive Sample:HeLa,Jurkat,U-87MG,Mouse thymus
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane.
Calculated MW:68kDa
Observed MW:68kDa/72kDa

The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:55054
Clone Number:ARC0812
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using ATG16L1 Rabbit mAb (CAB3637) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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