The ATG16L1 Rabbit Monoclonal Antibody (CAB3637) is a specialized tool for research involving ATG16L1, a key autophagy-related protein involved in cellular homeostasis and immune regulation. This antibody, generated from rabbit-derived mononclonal cells, exhibits high specificity and reactivity with human samples, making it ideal for use in Western blot applications.ATG16L1 is a crucial component of the autophagy pathway, contributing to the degradation of intracellular components and the maintenance of cellular health. Dysregulation of ATG16L1 has been implicated in various diseases, including inflammatory disorders, infectious diseases, and cancer.
As such, the ATG16L1 Rabbit Monoclonal Antibody serves as a valuable tool for studying the role of ATG16L1 in these pathological conditions.By enabling the detection and analysis of ATG16L1 protein expression in different cell types, this antibody supports research in immunology, cancer biology, and autophagy-related fields. Its reliable performance and specificity make it an essential reagent for investigating the functions and mechanisms of ATG16L1 in health and disease.
Product Name:
ATG16L1 Rabbit Monoclonal Antibody
SKU:
CAB3637
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 6-105 of human ATG16L1 (Q676U5).
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55054
Clone Number:
ARC0812
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ATG16L1 Rabbit mAb (CAB3637) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
